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Find cheap flights from Detroit to South Carolina from $38

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 7/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
dv. 7/12
dv. 7/19

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Best South Carolina Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$104
Myrtle Beach
Myrtle Beachnonstop$43
Greenville
Greenville1 stop$253
Columbia
Columbia1 stop$346
Florence
Florence1 stop$322
Augusta
Augusta1 stop$198

Good to know

Low season

January

High season

May

Cheapest flight

$38
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Detroit to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South Carolina from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South Carolina with an airline and back to Detroit with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South Carolina from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $173 one-way - $326 round-trip
  • Morning departure is around 3% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Detroit to South Carolina

Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10000 reviews
7.4Food
8.6Crew
7.9Comfort
8.2Boarding
8.0Entertainment
Airline reviews

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

2.0 MediocreFelipe, Jun 2024DTW - SAN
Read more about Delta reviews

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

Boarding was chaotic. I didn’t finish dinner because I went to bed early. Breakfast omelet was overcooked and tasteless but croissant was better than usual. Plane was dirty—crumbs in every seam and lavatory was poorly maintained (paint peeling, etc.) and toilet paper had not been refreshed before takeoff. No cubby for storage in first and seat was narrow.

The pilots were good. Disappointing when planes don't have electrical ports

Wifi wasn’t working well so we couldn't view any media.

Food service was bare-bone. Better bot to have any at all rather than hand out premade coffees and cookies to random few passengers.

Crew was great. Friendly, calm, interesting, happy to be there. That makes a huge difference. Plane was very quiet. Also quite empty so I had three seats to sleep across

Had assistance at airport getting from arrivals gate to departure gate; I couldn't have managed without that extra help. Thank you Delta.

They charge me for the luggage which is was included on the ticket

More space in the cabin. The guy in front of me leaned his seat back and I felt he was sitting in my lap.

Was a great smooth flight from Detroit to San Diego.

They put me on a chair in between two men, one overweight who was almost falling on top of me, and the other was even uncomfortable because I was half falling because of what the other was pushing me. I stayed with. my feet were swollen from fluid retention and from being unable to accommodate myself. it was very uncomfortable. I asked for help but they told me that the flight was full and they couldn't help me. I got off the plane almost unable to walk due to the inflammation. and then at FLL airport I asked for help because I couldn't go to my next flight, which was a connection.

The walk from baggage claim to the taxi is very difficult for older people I will never fly into JFK again. It is physically challenging

Overall fine but both ways for this trip was delayed.

Flight was delayed by almost 5 hours. Suitcase was not loaded despite the flight being near empty (my colleagues’ suitcases did reach JFK, unlike mine). Had to argue on phone to get JetBlue to deliver the case to my hotel. Never again

The flight was excellent. The crew was welcoming and attentive.

Great! I love Jet Blue. My favorite airline! Very efficient, clean and timely.

Run out of snack choices. Why are the seats not padded for your butt? Are we sitting on blocks of wood or metal for $250-300 a pop? This ain’t spirit. Let’s get it together people

We were told that our flight would be delayed for 90+ minutes because of weather, so we went to get something to eat only to have them randomly start boarding 15 minutes after the announcement, with no warning.

Entertainment... No earphones passed out. Many including me couldn't use the TV. Legroom was good. Crew was indifferent and a bit surly. Free wifi was a nice convenience. Check in desk location was unknown. Gate number on the boarding passes was wrong.

Going through JFK’s security is a mess. The TSA security said no shoes on the bins. So, we place our shoes in the belt and they came out all over the belt. Boarding was delayed and Flight as well.

Paid for premium economy had no tv the whole time the crew tried to reset/reboot but would not work they said they would put a trouble ticket in for it. We had 3 seats my tv was the only one that didn't work. They cancelled our flight re worked us on another that left us at airport over night on the floor I have a ten year old and a 78 diabetic mother which also had shingles and suffers from nerve pain in legs and back. Requested wheelchair service at all airports after the re route NO wheelchair service was there to help. WORST experience we have ever had. Went to American airlines assistance it was closed. I AM FURIOUS!!! I expect some sort of compensation from this traumatic experience and no need for flying points we don't plan on using American airlines again!!!!

This is by far the worst experience I have had with American Airlines. The start of this trip was a complete disaster. I purposely planned my trip so that I would weather any delays so that I could make very important meeting at the Pentagon. My flight was cancelled because of maintenance and I was put on the first flight the next day but I was late to the meeting. After a long week at the Pentagon I just wanted to go home and my flight home which was early in the day was delayed. Eventually the flight was delayed until the next day. I was not authorized a hotel room because DCA was my point of origin. So I paid for a hotel out of pocket. The flight this morning was boarded then deplaned because the aircraft was hot. The flow of information was not happening in DCA and made it worse when the news was bad. I am going to take a break from American for my next few military flights. Hopefully whatever has been going on with American Airlines will be resolved.

We had a 2 hour delay. The seats were smaller than most other airlines. The person in front of us wanted to lay back and we had to stop her because she was pressing against my girlfriend’s legs. We had to ask her to sit up and not lay back due to the lack of room.

Everything was fine once we actually got on our flight. It was more then annoying they canceled (delayed) our flight. We lost out on a day of our trip along with money on our stay. Plus we had to book another hotel. So expensive.

This flight was canceled and delayed several times without explanation. The plane was freezing cold and no wifi for messaging. Getting off the plane was terribly unorganized and felt like it took forever….

The flight was delayed several times without explanation. The seats were terribly uncomfortable and wifi isn’t included. All these make for a less than ideal flight.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

Internet service was erratic. Crew service was poor and slow. My luggage on this non-stop flight was lost and not recovered

Terrible. I didn’t fly and I had an important meeting the next day.

Equipment swap led to 2+ hour delay on international flight. And to top it off, boarding took forever.

The flight was very turbulent. The who 3 hours we mostly needed seat belts. Plane is older and does not have tv screens so no entertainment.

Experienced flight cancelations and delays in 5 days. They seem pretty common to AC. Experienced with one of AC's check-in agents at the counter of a big liar. She lied and acted (yes like acting in a movie) that an early flight was fully booked and refused to rebook me, but my flight was delayed two hours so I could not make my connection. Later, I got help at the gate to switch the early flight (Big thanks to that agent). Ater boading, I found the early flight was only 2/3 full meaning there was almost one vacant seat in a 3-person seater, and multiple empty 3-seaters. AC is wired that it is filled with good and bad employees. BTW, AC employees seem never smile, or they don't know how.

I appreciated the flight was on schedule but the crew told us that the flight would be delayed because of an air craft queue to take off. Instead of us arriving at 11.55pm, we were in Toronto at something past 2am which was a massive disadvantage on my part.

Not much food/snacks. I had just tea and it was so bitter.

My husbands flight last night Vancouver/Sydney was 90 minutes late in leaving. My flight tonight Vancouver/Seattle was also late in departing.

My mother, 80years old, had arranged for wheelchair assist to and from the aircraft cabin and in the airport but, no one showed up for her to de-plane. Apart from Air Canada having a reputation of being late for every leg of its flight so nothing was new this time so this time they did worse by not assisting seniors. I guess our whole family is done with this airline

Flights delayed over 4 hours with no compensation. No agents at counters to assist with re-booking.

Seating for almost 3 hours in the plan before aircraft takeoff. Very exhausted .

The bathroom did not have hand soap. That is unacceptable.

The only problem I encountered was they changed the gate on me while I was sitting down but no one notified me, they had sent me an email and by coincidence I checked it and found out that they had changed my boarding terminal. No one notified me and when I had asked the lady she told me yes this is the spot while they had already changed to another gate/terminal

Terrible leg room, seats don’t recline, delayed flight, and even water isn’t free onboard

Seats are very small and extremely hard. Too close together. The person next to me had average shoulders and was very far into my 'space'.

They didn’t let me get my boarding pass through the app because I have a lap infant. The ticket said to see a gate agent but there was no gate agent available. I was supposed to go to the kiosk. Ended up missing my flight and they said that I never checked in to my flight so there was nothing that could be done. I will never fly spirit again. Not even worth the hassle and poor customer service.

Cancelled my flight , currently stuck in Houston and will likely miss my cruise

The price is good but I feel that carry-on bag could be a little low and snacks prices

Pack light and enjoy the quick boarding and early departure and arrivals.

Passengers play their phones so everyone can hear them. No one tells them to use earbuds. Very annoying and unenjoyable.

I liked how we boarded early to combat all the chaos from people bringing oversized personal item luggage. It's so painful watching the process and feeling overwhelmed by the process.

Spirit Airlines has the worst customer service. I don't advise flying with them.

great customer service at the boarding gate that was warm and friendly. the flight experience with no complaints and the attendants were caring and attentive

Book cheap flights from Detroit to South Carolina

Recent round-trip flight deals

8/27dt.
1 stopSpirit Airlines
6h 01mDTW-MYR
8/28dc.
nonstopSpirit Airlines
1h 55mMYR-DTW
$56
8/21dc.
nonstopSpirit Airlines
1h 52mDTW-MYR
8/27dt.
nonstopSpirit Airlines
1h 55mMYR-DTW
$67
8/14dc.
1 stopFrontier
9h 07mDTW-CLT
8/21dc.
1 stopFrontier
9h 05mCLT-DTW
$105
8/31ds.
1 stopFrontier
7h 38mDTW-CLT
9/7ds.
1 stopFrontier
5h 47mCLT-DTW
$108
8/21dc.
1 stopDelta
5h 24mDTW-MYR
8/27dt.
nonstopDelta
1h 57mMYR-DTW
$129
8/21dc.
1 stopDelta
4h 11mDTW-MYR
8/27dt.
1 stopDelta
6h 42mMYR-DTW
$138
9/14ds.
1 stopAmerican Airlines
4h 48mDTW-MYR
9/28ds.
2 stopsAmerican Airlines
9h 11mMYR-DTW
$163
8/9dv.
1 stopAmerican Airlines
4h 31mDTW-MYR
8/12dl.
1 stopAmerican Airlines
4h 18mMYR-DTW
$188
8/14dc.
1 stopUnited Airlines
4h 10mDTW-CHS
8/20dt.
2 stopsUnited Airlines
8h 04mCHS-DTW
$253
8/13dt.
1 stopUnited Airlines
12h 31mDTW-SAV
8/16dv.
1 stopUnited Airlines
13h 51mSAV-DTW
$349

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Recent one-way flight deals

7/9dt.
nonstopSpirit Airlines
1h 53mDTW-MYR
$38
9/10dt.
1 stopSpirit Airlines
8h 38mDTW-CLT
$39
8/13dt.
1 stopFrontier
10h 12mDTW-CLT
$70
6/22ds.
1 stopFrontier
5h 19mDTW-CLT
$78
7/1dl.
nonstopAmerican Airlines
1h 52mDTW-CLT
$129
7/2dt.
nonstopDelta
2h 02mDTW-CHS
$154
7/3dc.
nonstopDelta
1h 44mDTW-CLT
$159
8/12dl.
nonstopAmerican Airlines
1h 53mDTW-CLT
$164
8/11dg.
1 stopUnited Airlines
4h 31mDTW-CLT
$167
9/17dt.
1 stopUnited Airlines
28h 34mDTW-GSP
$207

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Last minute flights from Detroit to South Carolina

Last minute flight, train and bus deals

6/15ds.
nonstopSpirit Airlines
1h 53mDTW-MYR
6/19dc.
nonstopSpirit Airlines
2h 03mMYR-DTW
$159
6/16dg.
nonstopSpirit Airlines
1h 53mDTW-MYR
6/18dt.
nonstopSpirit Airlines
2h 03mMYR-DTW
$166
6/13dj.
multi-stopFrontier
13h 36mDTW-CLT
6/17dl.
multi-stopFrontier
20h 28mCLT-DTW
$248
6/15ds.
multi-stopFrontier
5h 19mDTW-CLT
6/22ds.
multi-stopFrontier
13h 59mCLT-DTW
$278
6/14dv.
multi-stopAmerican Airlines
6h 02mDTW-MYR
6/16dg.
multi-stopAmerican Airlines
5h 00mMYR-DTW
$368
6/12dc.
multi-stopAmerican Airlines
4h 06mDTW-CHS
6/18dt.
multi-stopAmerican Airlines
4h 28mCHS-DTW
$383
6/13dj.
multi-stopUnited Airlines
6h 44mDTW-MYR
6/17dl.
multi-stopUnited Airlines
9h 39mMYR-DTW
$427
6/15ds.
multi-stopUnited Airlines
4h 35mDTW-MYR
6/17dl.
multi-stopUnited Airlines
9h 39mMYR-DTW
$443
6/13dj.
nonstopDelta
2h 01mDTW-CHS
6/14dv.
nonstopDelta
2h 04mCHS-DTW
$469
6/13dj.
multi-stopDelta
4h 59mDTW-CHS
6/14dv.
nonstopDelta
2h 04mCHS-DTW
$479

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Detroit - South Carolina Flights