Find flights
When to book
FAQs & Tips
Direct Flights
Deals

EYW

$148 Find cheap flights from South Carolina to Key West

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Key West departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Fri 6/21
Fri 6/28

Search hundreds of travel sites at once for deals on flights to Key West

In the last 7 days travelers have searched 43,423,329 times on KAYAK, and here is why:

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Good to know

Low season

September

High season

March

Cheapest flight

$148
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Myrtle Beach to Key West

FAQs for booking flights from South Carolina to Key West

  • How does KAYAK find such low prices on flights from South Carolina to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Key West?

Find which airlines fly direct from South Carolina to Key West, which days they fly and book direct flights.

Nonstop departures

South Carolina to Key West

Monday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Tuesday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Wednesday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Thursday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Friday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Saturday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Sunday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

See more direct flights

Nonstop returns

Key West to South Carolina

Monday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Tuesday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Wednesday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Thursday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Friday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Saturday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Sunday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Key West

Recent round-trip flight deals

7/20Sat
1 stopAmerican Airlines
6h 56mGSP-EYW
7/23Tue
1 stopAmerican Airlines
4h 40mEYW-GSP
$225
7/25Thu
1 stopDelta
4h 09mGSP-EYW
7/30Tue
1 stopDelta
5h 52mEYW-GSP
$248
8/26Mon
1 stopAmerican Airlines
6h 53mGSP-EYW
8/30Fri
1 stopAmerican Airlines
6h 18mEYW-GSP
$270
8/26Mon
2 stopsAmerican Airlines
7h 55mGSP-EYW
8/30Fri
1 stopAmerican Airlines
7h 08mEYW-GSP
$275
8/1Thu
1 stopDelta
3h 34mGSP-EYW
10/2Wed
1 stopDelta
6h 15mEYW-GSP
$278
8/26Mon
2 stopsAmerican Airlines
7h 55mGSP-EYW
8/30Fri
2 stopsAmerican Airlines
8h 38mEYW-GSP
$280
7/25Thu
1 stopAllegiant Air
24h 08mCHS-EYW
7/29Mon
1 stopAllegiant Air
11h 04mEYW-CHS
$311
6/4Tue
2 stopsUnited Airlines
23h 48mCLT-EYW
6/11Tue
2 stopsUnited Airlines
10h 54mEYW-CLT
$433
7/2Tue
1 stopUnited Airlines
7h 09mCLT-EYW
7/3Wed
2 stopsUnited Airlines
26h 49mEYW-CLT
$450
6/20Thu
1 stopAllegiant Air
20h 09mCHS-EYW
6/24Mon
1 stopAllegiant Air
10h 46mEYW-CHS
$506

Search by stops

Search by airline

Search by price

Recent one-way flight deals

5/29Wed
2 stops
20h 00mMYR-EYW
$148
5/29Wed
3 stops
21h 08mMYR-EYW
$156
6/15Sat
2 stops
23h 16mCLT-EYW
$186
8/10Sat
2 stops
20h 50mCLT-EYW
$193
8/10Sat
nonstopAmerican Airlines
2h 21mCLT-EYW
$203
8/10Sat
1 stopAmerican Airlines
4h 18mCLT-EYW
$213
9/30Mon
nonstopAmerican Airlines
2h 16mCLT-EYW
$218
9/10Tue
2 stopsUnited Airlines
19h 00mCLT-EYW
$219
9/30Mon
1 stopDelta
5h 15mCLT-EYW
$228
8/21Wed
2 stopsUnited Airlines
15h 00mCLT-EYW
$270

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Key West

Last minute flight, train and bus deals

5/23Thu
multi-stopAmerican Airlines
5h 18mMYR-EYW
5/28Tue
multi-stopAmerican Airlines
6h 46mEYW-MYR
$318
5/23Thu
multi-stopAmerican Airlines
8h 17mMYR-EYW
5/28Tue
multi-stopAmerican Airlines
4h 04mEYW-MYR
$418
5/23Thu
multi-stopAmerican Airlines
8h 17mMYR-EYW
5/28Tue
multi-stopAmerican Airlines
6h 26mEYW-MYR
$531
5/25Sat
multi-stopAmerican Airlines
5h 54mMYR-EYW
5/27Mon
multi-stopAmerican Airlines
8h 07mEYW-MYR
$537
5/26Sun
multi-stopUnited Airlines
9h 25mCLT-EYW
5/29Wed
multi-stopUnited Airlines
26h 40mEYW-CLT
$554
5/26Sun
multi-stopUnited Airlines
9h 25mCLT-EYW
5/29Wed
multi-stopUnited Airlines
6h 16mEYW-CLT
$581
5/22Wed
multi-stopUnited Airlines
6h 52mCLT-EYW
5/25Sat
multi-stopUnited Airlines
6h 16mEYW-CLT
$583
5/23Thu
multi-stopDelta
4h 31mSAV-EYW
5/27Mon
multi-stopDelta
6h 59mEYW-SAV
$728
5/24Fri
multi-stopDelta
4h 48mCLT-EYW
5/27Mon
multi-stopDelta
6h 19mEYW-CLT
$807
5/25Sat
multi-stop
17h 32mCLT-EYW
5/27Mon
multi-stop
24h 36mEYW-CLT
$1,108

Search by stops

Search by airline

Search by price

Flights to Key West

Destination:

Key West (EYW)United States

Return flight deals:

Key West - South Carolina

Cabin classes: