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ECP - TYS

$283 Find cheap flights from Panama City, Florida to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Knoxville departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/29
Sat 7/6

Search hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Knoxville, as well as popular online travel agencies
In the last 7 days travelers have searched 42,686,544 times on KAYAK, and here is why:

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Cheap flight deals from Panama City to Knoxville (ECP-TYS)

 
These are the cheapest deals for flights from Panama City to Knoxville currently on KAYAK along with options from the most popular airlines KAYAK users selected for this route. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Panama City to Knoxville

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Panama City to Knoxville.

Recent one-way flight deals from Panama City to Knoxville

Only flying one-way? Below are some of the best one-way flight deals from Panama City to Knoxville found on KAYAK recently.

Recent last minute flight deals from Panama City to Knoxville

Leaving soon but still want a bargain? Check out these latest deals for last minute flights from Panama City to Knoxville.

Recent direct flight deals from Panama City to Knoxville

The latest deals for direct flights from Panama City to Knoxville so you can sit back and relax without the need for a layover.

Cheap bus & train deals from Panama City to Knoxville

Find recent round-trip train or bus tickets from Panama City to Knoxville.

All round-trip flight deals to Knoxville

The cheapest plane tickets to Knoxville found on KAYAK recently.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
10:18 am - 3:45 pmECP-TYS
4h 27m1 stop
11:05 am - 4:11 pmTYS-ECP
6h 06m1 stop
$405American Airlines
Find Deal
Wed, Aug 7 - Fri, Aug 9
2:41 pm - 7:09 pmECP-TYS
3h 28m1 stop
12:43 pm - 6:01 pmTYS-ECP
6h 18m1 stop
$485American Airlines
Find Deal
Fri, Jul 12 - Sun, Jul 14
11:10 am - 2:49 pmECP-TYS
2h 39m1 stop
5:20 am - 8:16 amTYS-ECP
3h 56m1 stop
$488Delta
Find Deal
Sat, Oct 12 - Sat, Oct 19
2:41 pm - 11:59 pmECP-TYS
8h 18m2 stops
2:42 pm - 6:01 pmTYS-ECP
4h 19m1 stop
$490American Airlines
Find Deal
Fri, Jul 12 - Sun, Jul 14
11:07 am - 5:40 pmECP-TYS
5h 33m1 stop
12:44 pm - 6:29 pmTYS-ECP
6h 45m1 stop
$515American Airlines
Find Deal
Wed, Jun 12 - Wed, Jun 19
2:31 pm - 9:38 pmECP-TYS
6h 07m1 stop
5:12 am - 10:22 amTYS-ECP
6h 10m1 stop
$525American Airlines
Find Deal
Wed, Jun 12 - Thu, Jun 20
5:08 pm - 10:41 pmECP-TYS
28h 33m2 stops
7:00 am - 9:57 pmTYS-ECP
15h 57m2 stops
$620United Airlines
Find Deal
Sat, Oct 12 - Sat, Oct 19
6:52 am - 8:10 pmECP-TYS
12h 18m1 stop
7:00 am - 8:07 pmTYS-ECP
14h 07m2 stops
$625United Airlines
Find Deal
Wed, Jun 12 - Wed, Jun 19
5:12 pm - 10:14 amECP-TYS
16h 02m2 stops
5:45 pm - 4:22 pmTYS-ECP
23h 37m2 stops
$634United Airlines
Find Deal
Wed, Aug 7 - Fri, Aug 9
7:05 am - 8:59 pmECP-TYS
12h 54m2 stops
5:25 am - 10:22 amTYS-ECP
5h 57m1 stop
$779Delta
Find Deal
Wed, Jun 12 - Sat, Jun 15
2:31 pm - 9:38 pmECP-TYS
6h 07m1 stop
$283American Airlines
Find Deal
Fri, Jun 28
2:31 pm - 11:59 pmECP-TYS
8h 28m2 stops
$288American Airlines
Find Deal
Fri, Jun 28
12:50 pm - 7:00 pmECP-TYS
5h 10m1 stop
$313American Airlines
Find Deal
Fri, Jun 21
12:50 pm - 7:00 pmECP-TYS
5h 10m1 stop
$343American Airlines
Find Deal
Wed, Jun 12
12:50 pm - 11:59 pmECP-TYS
10h 09m2 stops
$348American Airlines
Find Deal
Wed, Jun 12

Good to know

Low season

September

High season

October

Cheapest flight

$283
Best time to beat the crowds with an average 44% drop in price.
Most popular time to fly and prices are also 36% lower on average.
Flight from Panama City to Knoxville

When to book flights from Panama City to Knoxville

Are your dates flexible? Find out the best times to travel from Panama City to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Knoxville

  • What is the cheapest flight from Panama City, Florida to Knoxville?

    In the last 3 days, the lowest price for a flight from Panama City, Florida to Knoxville was $283 for a one-way ticket and $405 for a round-trip.

  • Do I need a passport to fly between Panama City and Knoxville?

    A passport is not required to fly from Panama City to Knoxville.

  • Which airports will I be using when flying from Panama City to Knoxville?

    Panama City and Knoxville are both served by 1 main airport. You will leave Panama City from Panama City NW Florida Beaches and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Panama City to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Knoxville?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Knoxville are Delta and American Airlines. With an average price for the route of $481 and an overall rating of 8.0, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $650 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Panama City to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Panama City with another airline. Booking your flights between Panama City and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top airlines flying from Panama City to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10457 reviews
8.6Crew
8.2Boarding
8.0Entertainment
7.9Comfort
7.4Food
Airline reviews

Rated entertainment as Mediocre as there were major problems with the Infotainment system that took probably a half hour for them to fix.

8.0 Excellentrghinftl, May 2024FLL - BOS
Read more about Delta reviews

Rated entertainment as Mediocre as there were major problems with the Infotainment system that took probably a half hour for them to fix.

Delta crushed it. Flight attendant in first was attentive and just never stopped. Honestly one of the best domestic flights I’ve been on.

The 1st class male crew member was very pleasant - the short female with round glasses , maybe in 50’s had no personality- never spoke when delivering my food, drink, & never smiled the whole trip! In fact looked annoyed when the boarding proses was happening- I would never hire this woman - unfriendly . Have never dealt with a crew member like her-

Best airline! Always friendly and welcoming. Skyclub was great and loved the fast free wifi on board. I also love that you can pre-order your meal on the app!

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

I liked the ease of checking in, luggage check in, wheel chair assistance, boarding and flight.

The main person that was coordinating everything was a short white/light skin Spanish man and he was very rude. It honestly made me feel like it was everyone’s First day at work. His announcements were very not reasonable and they did not make sense. The stewardess on the flight that made the announcements she didn’t even know what she was talking about she sounded inebriated. There were no snacks or drinks on our flight there wasn’t even much turbulence. This flight was not enjoyable nor was it what a Delta flight should be and just this past week I flew with Delta 3 times.

nothing Delta could do... the person sitting next to me was huge and overflowing into my seat

Crew was great! I need wheelchair assistance and they knew who I was and updated me that my chair was on its way and to just hang tight. There was some turbulence but the captain announced we would be going thru it and he handled the plane well. Landing was soft and his.

Was lucky to have a employee at the AA checkin counter that had compassion and understood they ordeal that we went through with our original flight being diverted, needing to stay in the aircraft and then flying to the original destination; adding hours to the trip and forcing us to miss our connection and our rebooked connection. She was able to get up on standby on the highest priority on the next flight to the closest airport we need to be at and it all worked out despite being many hours late.

Delayed so that missed connecting flight. Connecting flight was also delayed on the tarmac but they closed the gate before the rescheduled time.

Took off over an hour late with multiple mechanical issues. Gate agent in Dallas was lazy and was slow as molasses. Had a line 10 people long. Spirit bad..

They gave my seat away although it was a connecting flight with them and the flight was a bit delayed.

The Flight attendant had an attitude and didn't allow anyone any time to prepare for landing despite being absent throughout the entire trip

Horrible people at the gate, they force me to check in my carry on, even thought no one behind me has to do it. I had to get out of the airport in NY to get my bag and go thru security again on my way to Honk Kong. The worst part is the employee threatened me with loosing the flights if don’t comply.

Delayed flight, few announcements with information, no comps, cluster f boarding because zones weren’t spread out and announced loud and repeatedly, staff did their job -nothing more nothing less, annoying kids were speaking and kicking the heck out of the back of my seat and parents weren’t willing to parent… so another typical day of air travel in the US.,

Flight was delayed until Next day as crew timed out

The flight was great until towards the end when the flight attendant read an excessively long commercial for purchasing an american airlines credit card. The worst part is that we are doing a lot of traveling this year so i was actually interested in getting the credit card, but I was so annoyed with the long commercial that I completely dismissed the flight attendant bringing around the information. Next time, keep the sales pitch to 10 seconds and then pass around the brochures!!

I was able to get on standby with relative ease

Book cheap flights from Panama City to Knoxville

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Panama City to Knoxville found on KAYAK in the last 72 hours.
6/28Fri
1 stopAmerican Airlines
6h 07mECP-TYS
$283
6/28Fri
2 stopsAmerican Airlines
8h 28mECP-TYS
$288
6/21Fri
1 stopAmerican Airlines
5h 10mECP-TYS
$313
6/12Wed
1 stopAmerican Airlines
5h 10mECP-TYS
$343
6/12Wed
2 stopsAmerican Airlines
10h 09mECP-TYS
$348

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Panama City - Knoxville Flights

Departure:

Panama City (ECP)United States

Destination:

Knoxville (TYS)United States

Return flight deals:

Knoxville - Panama City

Cabin classes: